Church of Neuroscience L3C aka K&B Organics: Sacred Substances for Joyful, Free, Inquisitive Spirits & Minds
"There is a part of us that longs for something tangible [that reminds us of, and connects us to, The Divine Creator(s)/The Grand Architect(s)/God] that....interacts with the senses. The sacraments, those sacred mixtures of matter and the Holy Spirit, fulfill that need." From: 'The Sacramentals: What are they? Regina Doman. EWTN Global Catholic Television Network; http://www.ewtn.com/library/answers/whatare.htm (accessed 03/16/2013).
WEDNESDAY, DEC 4th UPDATE: HAPPY HOLIDAYS
Educational Primer on the Sacred Benzofurans (6-APB, 5-APB, 6-APDB, 5-APDB, 5-MAPB)
History/Development: Following the banning of Mephedrone (4-MMC) in April 2010 in the UK a group of UK vendors came together to form the Association of Independent Research Chemical Retailers (AIRCR). The AIRCR went to work on developing substances that would be superior Controlled Dangerous Substances such as MDMA. In late 2010, the AIRCR began offering 6-APB. Later, 5-APB and 5-MAPB were also offered before the sale (but not possession) of these substances was restricted under UK law. The development of the Sacred Benzofurans has been aided by the fact that benzofuran variants such as 6-APDB & 5-APDB had already been synthesized and tested with rodent models in the mid-1990's by Nicholls et al. at Purdue University during their research on non-neurotoxic 'analogs' of MDMA and MDA.
Pharmacology: The Sacred Benzofurans are generally thought to act by increasing the release of serotonin, norepinephrine, and dopamine as well as by inhibiting their re-uptake. Of course, the precise mechanism of action is not currently known and may ultimately be unknowable -- as is also true of commonly prescribed products such as Prozac, Wellbutrin, Celexa, and Seroquil.
Legal Status: The Sacred Benzofurans are unscheduled in the United States. Although they may appear to bear some similarity to MDA or MDMA at first glance, the substitution of the benzofuran ring results in a substantially dissimilar molecular / chemical structure compared to MDA--which, by extension, results in a substantially dissimilar psychopharmacological profile compared to MDA.
Medical Uses: It is believed that the Sacred Benzofurans are not neurotoxic (as opposed to MDA or MDMA which produce neurotoxicity through at least a dozen known mechanisms. Parishioner reports strongly suggest that the benzofuran ring substitution results in a psychoactive profile that is similar to MDA & MDMA but without the neurotoxic "comedown" associated with those Controlled Dangerous Substances. While MDMA does not currently have recognized medical uses in the United States the Multidisciplinary Association for Psychedelic Studies is currently undertaking a large set of FDA-sanctioned human research trials with MDMA.(which has the common street name "Ecstasy"). Paradoxically, while MDMA is not currently FDA approved for human consumption, human subject-based research with MDMA as a medical treatment is currently ongoing in the United States under FDA-approved research protocols. The growing body of scientifically gathered evidence from these trials strongly point to MDMA as a compound that, despite its neurotoxic potential, may help those who suffer from anxiety, depression, or post-truamatic stress (PTSD). MDMA also appears to have analgesic (pain relieving) effects for many users--an effect that in many cases lasts for up to several days after just one administration of MDMA. The apparent non-neurotoxic potential of the Sacred Benzofurans suggests that the potential of these compounds is much greater than that of MDMA for those suffering from anxiety, PTSD, and depression; many Parishioners report that the Sacred Benzofurans also have an analgesic effect similar to that of MDMA.
Other Uses: The enactogenic and entheogenic effects of the Sacred Benzofurans have lead to their use for religious purposes, use in groups for enhanced closeness and connectivity to others, use by couples seeking greater intimacy and closeness, and by those seeking to harness their creative potential.
Mis-use Potential: Based on what is known about the effects of benzofuran ring substitution in other compounds, as well as based on Parishioner reports over the past two (2) years, the mis-use potential of the Sacred Benzofurans is slight - and far below that of either MDA or MDMA. Parishioners have consistently reported that the Sacred Benzofurans are far less problematic than MDA & MDMA in terms of producing undesired effects. For example, ingestion of Sacred Benzofurans may elevate heart rate only slightly while MDA and MDMA can produce dramatic increases in heart rate. Likewise, while many Parishioners report that the Sacred Benzofurans do slightly elevate body temperature, the Sacred Benzofurans have not been reported to produce the profound dysregulation of body temperature associated with MDA and MDMA. Moreover, based on two (2) or more years of Parishioner reports, rather than leading to deficits in memory and cognition and/or emotional dysfunction, the Sacred Benzofurans, are widely reported to act as a nootropic substance that improves cognition and promotes emotional stability when used in a manner consistent with the Rites of Beneficence.
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